Enfermedad de Paget extramamaria perianal

Extramammary Paget Disease Treated With 5% Imiquimod Cream Enfermedad de Paget extramamaria tratada con imiquimod 5% crema

observed in scalp discoid lupus erythematosus. Arch Dermatol. 2009;145:1406--9. 4. Uysal AC, Alagöz MS, Unlü RE, Sensöz O. Hairdresser’s syndrome: a case report of an interdigital pilonidal sinus and review of the literature. Dermatol Surg. 2003;29:288--90. 5. Morrell JF. ‘‘Pilonidal’’ sinus of the sole. Arch Dermatol. 1957;75:269. 6. Sakai R, Higashi K, Otha M, Sugimoto Y, Ikoma Y, Horiguchi Y...

Fosforilación de tau y enfermedad de Alzheimer

Perianal Paget disease: a report of 2 cases

Extramammary Paget disease (EMPD) is a rare cutaneous neoplasm. Perianal Paget disease (PPD) is a subset of EMPD manifesting perianal lesions. Two cases of PPD in Severance Hospital are described in this article. A 65-year-old female and 78-year-old male patients visited our institution because of an unhealed perianal skin lesion despite treatment for a long period with topical agents. PPD was ...

La enfermedad de Huntington: una visión biomolecular

La enfermedad de Huntington (EH) es una afección neurodegenerativa de carácter autosómico dominante, con penetración completa, cuya prevalencia es de 5 a 10 casos por cada 100.000 habitantes [1-3]. Las manifestaciones clínicas aparecen con mayor frecuencia entre los 35 y los 50 años de edad y se caracterizan por un cuadro progresivo de movimientos anormales e involuntarios de tipo coreico, que ...

Extramammary Paget disease of the perianal region: the potential role of imiquimod in achieving disease control

Extramammary Paget disease (EMPD) is a rare perineal neoplasia associated with a high rate of local recurrence. Surgical excision is the standard treatment; however, this has high rates of post-operative morbidity in combination with potentially mutilating results. Previous literature has demonstrated good response with imiquimod 5% cream in patients with vulval EMPD, yet its effectiveness in p...